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Janson Beckett Cosmeceuticals, a leading developer of age-defying, peptide skin care products, today announced general availability of the cosmetic industry's most intense "spot-wrinkle treatment" - DermaExcel 7 (R).

DermaExcel 7 is the first cosmeceutical to combine skin care's three most advanced peptides - Argireline, Leuphasyl, and SNAP-7 - in one topical formulation. The peptides in DermaExcel 7 work collaboratively at the skin structure's neurotransmitter level, interrupting the wrinkle-producing SNARE complex. BOTOX, an injection-based treatment, targets and stops this same neurotransmitter process.

The Science and Art of Today's Cosmetics

DermaExcel 7 contains 5% Leuphasyl (PentaPeptide), 10% Argireline (HexaPeptide), and 10% SNAP-7 (HeptaPeptide). Leuphasyl interacts with the skin to lower its electrical charge, making it more difficult for the neurons that move muscles to fire. Argireline and SNAP-7 complement Leuphasyl, working in tandem to intercept the release of chemicals that trigger muscle contractions. By preventing the frequency and severity of muscle movements, the peptides in DermaExcel 7 significantly reduce wrinkle depth and even work to prevent their formation.

The launch of DermaExcel 7 is an extension to Janson Beckett's high-end, anti-aging product line and a continuation of its philosophy to develop skin care treatments that go beyond "wrinkle correction". Along with the peptides in its formulation, DermaExcel contains Alpha Lipoic Acid (a powerful antioxidant), DMAE (a skin firmer), and Shea Butter (a superior skin moisturizer) - ingredients proven to help rejuvenate skin, firming its tone and smoothing its appearance.

"We are proud to be on the front lines of the peptide revolution," stated Janson Beckett president Ian Strassler. "Today's consumers are savvy and understand that the science portion of skin care has advanced from simply enabling users to look good to actually facilitating changes to their skin. DermaExcel 7 is a major step forward in combating wrinkles aggressively, yet in an ultra-safe manner."

24% to 60% Wrinkle Reduction in 28 Days

Results of in vivo testing of formulations with Argireline and Leuphasyl conducted over 28 days showed an average of 24% reduction in "expression wrinkles", with a maximum value of nearly 47% attained. Formulations containing SNAP-7 spiked the test results, with maximum values topping an impressive 60% wrinkle reduction. In non-clinical Janson Beckett user trials conducted on 200 volunteers in September 2005, subjects reported seeing quick improvements, typically noting immediate skin tightening and an invigorating tingling sensation for up to 30 minutes after application of DermaExcel 7.

DermaExcel 7 (1 ounce) has an MSRP of $159.95 and is available through select retailers, including SkinStore.com. SkinStore.com represents over 2,000 products from more than 120 of the finest physician recommended, spa, and department store brands. Janson Beckett's DermaExcel 7 product was featured in SkinStore's Times Square advertising campaign that ran November 17-30 on NBC's massive 30 ' x 40' AstroVision Video Screen (42nd and Broadway).

In July of 2004, Janson Beckett introduced AlphaDerma CE -- the first BOTOX alternative to blend the corrective peptide Argireline with Alpha Lipoic Acid, DMAE, Vitamin C Ester, Collagen, Elastin, and Soy. Escalating in popularity within diverse segments of the skin care market, including spas and dermatology/laser centers, AlphaDerma CE was recently included in the Celebrity Gift Bag of the 2005 American Music Awards, held November 22 in Los Angeles.

ABOUT JANSON BECKETT COSMECEUTICALS

Janson Beckett Cosmeceuticals develops and manufactures advanced peptide skin care products for age and image conscious consumers. Information on the company and its products can be found at www.janson-beckett.com.

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